Dried Aluminium Hydroxide + Magnesium Trisilicate Tablets

Description

Dried Aluminium Hydroxide & Magnesium Trisilicate Tablets

(Compound Magnesium Trisilicate Tablets BP, where the registered formulation meets the applicable monograph)

Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified)
Exported by: Healthy Inc (Star Export House)

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a manufacturer of Dried Aluminium Hydroxide and Magnesium Trisilicate Tablets in India. This non-systemic antacid combination neutralizes gastric acid and may provide short-term symptomatic relief from heartburn, acid indigestion and hyperacidity. Antacids relieve symptoms but do not by themselves treat the underlying cause of persistent dyspepsia, peptic ulcer disease or recurrent reflux symptoms.

Contract manufacturing and institutional packaging can be configured according to the approved product specification, destination-market registration and procurement requirements.

2. Product Specifications

3. Manufacturing Technology

• Granulation & Compression: High-dose mineral ingredients require controlled granulation and compression to achieve the registered hardness, friability, weight and tablet-performance specifications.
• Palatability: Raw-material particle size and formulation design can be controlled to improve mouthfeel in chewable dosage forms.
• Aluminium/Magnesium Combination: Combining aluminium and magnesium salts may balance some gastrointestinal effects, but it does not guarantee a neutral effect on bowel motility in every patient.
• Packaging: Blister, bulk and institutional presentations may be supplied where supported by stability and market requirements.

4. Quality Assurance

• Acid-Neutralizing Capacity: Where required by the applicable monograph/specification, acid-neutralizing capacity is tested using the registered method and acceptance criteria.
• Identity & Assay: Mineral components are tested against applicable pharmacopoeial or registered specifications.
• Elemental Impurities: Relevant elemental impurities, including those associated with mineral raw materials, are controlled according to applicable specifications and regulatory requirements.
• Stability: Shelf life and storage conditions are supported by product-specific stability data.

5. Pharmacology and Clinical Use

Aluminium hydroxide and magnesium trisilicate react with gastric acid and increase gastric pH. Magnesium trisilicate can also form hydrated silica products during acid neutralization. The combination is intended primarily for symptomatic antacid action.

• Heartburn / Acid Indigestion: May provide temporary relief of symptoms associated with excess gastric acidity.
• Gastritis / Dyspepsia Symptoms: May relieve acid-related discomfort, but persistent or recurrent symptoms warrant medical assessment.
• Peptic Ulcer Symptoms: Antacids may temporarily reduce acid-related pain but are not a substitute for diagnosis and appropriate ulcer treatment, including testing/treatment for H. pylori when indicated.

6. Export and Regulatory Support

• Dossier Support: CTD / ACTD documentation where applicable.
• Certificates: FSC, COPP and COA where applicable.
• Institutional Supply: Tender and bulk packaging can be configured according to approved specifications and procurement requirements.
• Logistics: Air or sea shipment via FOB Mumbai / CIF according to applicable requirements.

7. Frequently Asked Questions

Q: Who manufactures these tablets?
A: Healthy Life Pharma Pvt. Ltd. manufactures Aluminium Hydroxide and Magnesium Trisilicate tablet formulations in India.

Q: Is this the same as a particular branded antacid?
A: Brand formulations can contain different active ingredients and strengths. This product should not be described as equivalent to a specific brand unless composition and required regulatory equivalence are established.

Q: Why are chewable antacid tablets chewed?
A: Chewing disperses the tablet before swallowing and increases contact area, supporting the intended performance of a chewable antacid. Follow the exact product label.

Q: Can antacids interact with other medicines?
A: Yes. Aluminium- and magnesium-containing antacids can reduce absorption of medicines including some tetracycline/fluoroquinolone antibiotics, iron, levothyroxine and others. Required spacing differs by medicine, so follow the interacting medicine's label or professional advice rather than applying a universal two-hour rule.

Clinical Pharmacology & Safety Information

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

• Individualized Use: Number of tablets and frequency should follow the exact registered label, because strength and acid-neutralizing capacity can differ between products.
• Chewable Form: Chew thoroughly if the registered dosage form is a chewable tablet.
• Other Medicines: Review concomitant medicines for absorption interactions and apply medicine-specific separation intervals.
• Persistent Symptoms: Frequent, severe or persistent heartburn, unexplained weight loss, gastrointestinal bleeding, difficulty swallowing or recurrent pain requires medical evaluation rather than prolonged self-treatment.

9. Side Effects and Precautions

• Gastrointestinal: Aluminium salts can contribute to constipation and magnesium salts can contribute to diarrhea; individual response varies.
• Kidney Disease: Significant renal impairment increases the risk of aluminium or magnesium accumulation. Use should be medically supervised and may be inappropriate depending on renal function and the product label.
• Long-Term / High-Dose Use: Aluminium-containing antacids can reduce phosphate absorption and contribute to hypophosphatemia, particularly with prolonged or excessive use.
• Drug Interactions: Antacids can alter absorption of numerous medicines; medication review is important.

10. Storage Instructions

• Store below 30°C unless otherwise specified on the registered label.
• Keep in a dry place and protect from excessive moisture.
• Keep in original packaging and out of reach of children.