Composition: Isosorbide Dinitrate IP 5 mg / 10 mg; BP 5 mg (each uncoated tablet).
Additional separate products: Isosorbide Mononitrate 10 mg and M-Trate Isosorbide 5-Mononitrate BP 20 mg.
Usage: Prevention of angina-related chest pain.
Category: Anti Cardiovascular Drugs
Therapeutic Category: Cardiovascular Agent / Anti-anginal Nitrate
SKU: Isosorbide Tablets
Categories: Contract Manufacturer, Formulations Exporter India, Manufacturing Pharmaceutical Company India, Pharmaceutical Exporter India, Pharmaceutical Formulations India, Tablets Manufacturer, WHO GMP Certified Formulations
Isosorbide Dinitrate Tablets is listed in our pharmaceutical product portfolio for business-to-business enquiries. Product-specific formulation details, available strengths, dosage form, pack configuration and supply terms should be confirmed against the current product specification before ordering.
For distributor, wholesaler, hospital procurement and export enquiries, please request the applicable product specifications, batch documentation, shelf-life information, packaging options and regulatory documents. Availability and documentation depend on the product and destination market.
Healthy Life Pharma Pvt. Ltd. presents Isosorbide Dinitrate Tablets for the prevention of angina (chest pain). Isosorbide dinitrate is an organic nitrate vasodilator that relaxes blood vessels and reduces cardiac workload. The supplied catalogue also includes isosorbide mononitrate products; these contain a different active ingredient and are clearly identified separately.
Manufactured by: Healthy Life Pharma Pvt. Ltd. (WHO-GMP Certified, as supplied)
Exported by: Healthy Inc (Star Export House, as supplied)
| Product | Composition per tablet | Dosage form |
|---|---|---|
| Isosorbide Dinitrate Tablets IP 5 mg | Diluted Isosorbide Dinitrate IP equivalent to Isosorbide Dinitrate 5 mg | Uncoated |
| Isosorbide Dinitrate Tablets IP 10 mg | Diluted Isosorbide Dinitrate IP equivalent to Isosorbide Dinitrate 10 mg | Uncoated |
| Isosorbide Dinitrate Tablets BP 5 mg | Diluted Isosorbide Dinitrate BP equivalent to Isosorbide Dinitrate 5 mg | Uncoated |
| Isosorbide Mononitrate Tablets 10 mg | Diluted Isosorbide Mononitrate equivalent to Isosorbide Mononitrate 10 mg | Uncoated; separate active ingredient |
| M-Trate / Isosorbide 5-Mononitrate BP 20 mg | Diluted Isosorbide 5-Mononitrate BP equivalent to 20 mg | Uncoated; separate active ingredient |
Isosorbide dinitrate CAS: 87-33-2. Therapeutic class: Anti-anginal / organic nitrate vasodilator. Confirmed dinitrate strengths: 5 mg and 10 mg. 20 mg: confirmed only for the separate isosorbide 5-mononitrate M-Trate product, not for dinitrate. All supplied products are uncoated; no sublingual dosage form has been confirmed. Shelf life, pack sizes and pharmacopoeial compliance require product-specific verification.
Low-dose nitrate formulations require careful handling of the specified diluted active ingredient, controlled blending, content uniformity and validated compression. Processing methods, excipient compatibility and packaging selection should follow the approved formulation and safety procedures. A particular granulation method, sublingual performance or dangerous-goods classification should not be assumed without documented product evidence.
Appropriate release testing may include identity, assay, uniformity of dosage units, disintegration or dissolution, related substances and stability testing against the applicable approved IP/BP monograph and registration specifications. Exact numeric acceptance limits must be verified for each product.
Isosorbide dinitrate is converted to nitric oxide-related signaling species, promoting vascular smooth-muscle relaxation and reducing myocardial oxygen demand. It is used for angina prevention; some prescribed regimens may include it in heart-failure treatment with other agents. Isosorbide mononitrate is not interchangeable milligram-for-milligram with dinitrate. These listed oral tablets should not be presented as a verified emergency sublingual treatment for sudden chest pain.
For contract manufacturing and exports, request the product-specific certificate of analysis, approved composition, stability data, packaging details and registration dossier where available. FSC, COPP, CTD/ACTD documentation and country-specific approvals should be confirmed before commercial claims are made.
Q: Which isosorbide dinitrate strengths are listed?
A: IP 5 mg, IP 10 mg and BP 5 mg.
Q: Is M-Trate the same as isosorbide dinitrate?
A: No. The supplied M-Trate composition contains isosorbide 5-mononitrate 20 mg.
Q: Can these tablets treat a sudden angina attack?
A: Do not assume so. The supplied formulations are listed as uncoated oral tablets, not confirmed sublingual rescue products. Follow the patient’s emergency plan and seek urgent medical help for new, severe or persistent chest pain.
Q: Can nitrates be taken with sildenafil or tadalafil?
A: No. This combination can cause dangerous, potentially life-threatening hypotension.
Use only according to a qualified prescriber and the approved label. Dose, schedule and any nitrate-free interval depend on the exact formulation and indication. Do not substitute mononitrate for dinitrate or use an oral tablet under the tongue unless specifically approved for that route. Do not stop or change therapy without medical advice.
Store in the original packaging, protected from excess heat, moisture and light as specified on the approved pack label. Keep out of reach of children.