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Carbidopa and Levodopa Tablets

Carbidopa and Levodopa Tablets

Healthy Life Pharma

Carbidopa and Levodopa Tablets IP
Each Uncoated Tablet Contains:
Levodopa IP 100 mg
Carbidopa IP, as Anhydrous Carbidopa 10 mg

Combimet Tablets
Carbidopa and Levodopa Tablets IP
Each Uncoated Tablet Contains:
Carbidopa IP, Eq. to Anhydrous Carbidopa 25 mg
Levodopa IP 250 mg

Levodopa and Carbidopa Tablets 100 + 10 mg
Each Film Coated Tablet Contains:
Levodopa BP 100 mg
Carbidopa BP, as Anhydrous Carbidopa BP 10 mg
Titanium Dioxide
Excipients q.s.

Categories: Contract Manufacturer, Formulations Exporter India, Manufacturing Pharmaceutical Company India, Pharmaceutical Exporter India, Pharmaceutical Formulations India, Tablets Manufacturer, WHO GMP Certified Formulations

Product Information

Healthy Incorporation and Healthy life pharma Pvt ltd are one of the leading manufacturer,supplier, and exporter of Carbidopa with Levodopa tablets in India and serving the world with best quality pharmaceutical products.

Carbidopa with Levodopa tablets Manufacturer

Healthy incorporation and Healthy life pharma Pvt ltd, is Mumbai Based WHO GMP certified manufacturer of injection, tablets, capsules, liquid, dry syrups, pre-filled syringes, ointments etc. with an extensive experience of over 45 years in manufacturing and have reach in many countries.We are committed to provide a stock of highly effective Carbidopa with Levodopa tablets to our innumerable clients with the help of our well experienced pharmaceutical specialists.We supply this tablets in two different combinations:

  1. Carbidopa 10 mg + Levodopa 100 mg tablets

2. Carbidopa 25 mg + Levodopa 250 mg tablets

Carbidopa with Levodopa tablets is a combination of levodopa and carbidopa which is used to cure the symptoms of Parkinson disease and Parkinson like symptoms that may develop after encephalitis which means swelling of the brain or injury to the nervous system caused by poisoning of carbon monoxide.

Uses of Carbidopa with Levodopa tablets:

Carbidopa and levodopa combination is used to cure Parkinson disease, sometimes it is called as paralysis agitans or shaking palsy. Parkinson disease is an irregularity of the central nervous system. Dopamine is a normally occurring substance in the brain that helps in control of movements and activities like walking and talking. Parkinson patients do not have enough dopamine in some parts of the brain. This Levodopa get in brain and helps replace the missing dopamine, which helps people to function normal. It works by increasing the amount of dopamine in the brain, it is advisable to void a high protein diet (it reduces the amount of levodopa that your body takes in) during medication. This belongs to a class of medications called decarboxylase inhibitors

This medicine is available on doctor  prescription.

Additional Information of Carbidopa with Levodopa tablets:

Product Name                                                                    Carbidopa with Levodopa tablets

Composition & Active ingredients                               Carbidopa & Levodopa

Potency                                                                               Carbidopa 10 mg + Levodopa 100 mg

Carbidopa 25 mg + Levodopa 250 mg tablets

Therapeutic use                                                               Parkinson disease

Packing                                                                              10 Tablets (1 Box)

Dosage                                                                                As per Doctor Prescription

Precautions of Carbidopa with Levodopa tablets:

Please inform  doctor your medical history, especially of liver disease, glaucoma, heart disease ,heart failure, irregular heartbeat, kidney disease,  mental/mood disorders such as depression, suicidal thoughts or actions, blood disorders, sleep disorders. Consult your doctor if you are pregnant or planning to get pregnant or breast-feeding mother.

Side Effects of Carbidopa with Levodopa tablets:

Most of the time there is no serious side effects. Some Common side effects may arise after starting medication, as your body adjust to medicine.

  • Lack of appetite
  • Bladder pain
  • Nausea
  • Vomitting
  • Chest pain
  • Irregular heartbeat
  • Muscle/Joint pain
  • Depression/Anxiety
  • Insomnia
  • Dizziness
  • Nightmares
  • Hallucinations

For Detailed Product Information Contact Us at +91 7710003340, If you need Any assistance in selecting our Products that fits your requirements. If you are looking for any product that you are not seeing here, please contact our support team.

Note: Healthy Incorporation and Healthy life pharma Pvt ltd tries to ensure that all information, whether in relation to the products, services, offerings provided as part of this website is correct at the time of inclusion on the website, Unauthorized use of any materials contained on this website may violate copyright laws, trademark laws, the laws of privacy and publicity, certain communications statutes and regulations and other applicable laws and regulations. All copyright and other intellectual property rights in this material are owned by Healthy Incorporation. Please connect with us to discuss precise product specifications and requirements and obtain advice on which products are suitable for your requirement or you can write to info@healthyinc.co.in

Carbidopa and Levodopa Tablets is listed in our pharmaceutical product portfolio for business-to-business enquiries. Product-specific formulation details, available strengths, dosage form, pack configuration and supply terms should be confirmed against the current product specification before ordering.

For distributor, wholesaler, hospital procurement and export enquiries, please request the applicable product specifications, batch documentation, shelf-life information, packaging options and regulatory documents. Availability and documentation depend on the product and destination market.

Description

Carbidopa with Levodopa Tablets (10/100, 25/100, 25/250)

Manufactured by Healthy Life Pharma Pvt. Ltd. | Exported by Healthy Inc

1. Product Introduction

Healthy Life Pharma Pvt. Ltd. is a specialized manufacturer of Carbidopa and Levodopa Tablets in India. This combination is an established treatment for Parkinson’s disease. We manufacture Immediate Release (IR) formulations and, subject to validated formulation and market requirements, Controlled Release (CR) formulations for management of motor symptoms and dose-related fluctuations. Our facility adheres to WHO-GMP standards, while Healthy Inc manages global exports and neurology tenders.

2. Product Specifications

ParameterSpecification
Product NameCarbidopa & Levodopa Tablets
Generic NameCo-Careldopa / Levodopa + Carbidopa
Strength (Carbidopa / Levodopa)10mg/100mg / 25mg/100mg / 25mg/250mg / 50mg/200mg (CR option)
Dosage FormUncoated / Film Coated Tablet / Controlled Release (CR) Tablet
StandardUSP / BP / IP Compliant
Therapeutic ClassAnti-Parkinson (Dopamine Precursor + Decarboxylase Inhibitor)
Shelf Life36 Months
Packaging10×10 Alu-Alu Blister / 100s HDPE Bottle

3. Manufacturing Carbidopa & Levodopa Tablets

  • The Manufacturer: Healthy Life Pharma Pvt. Ltd. Healthy Life Pharma manufactures the product at a WHO-GMP certified plant in Mumbai. Levodopa is susceptible to oxidation, so controlled manufacturing conditions, suitable excipients and protective packaging are important for maintaining product quality. Functionally scored tablets may be developed where supported by the validated formulation and regulatory requirements.
  • The Exporter: Healthy Inc. Healthy Inc manages international trade and logistics for Carbidopa and Levodopa Tablets, including high-barrier packaging and documentation for international markets.

4. Quality Assurance

  • Dissolution Profiling: Immediate-release products are tested for appropriate rapid release, while modified-release products are tested against their specified release profile.
  • Appearance & Stability: Finished tablets are monitored during release and stability studies for physical changes that could indicate degradation.
  • Assay / Content Uniformity: Both active ingredients are tested to verify potency, content uniformity and the specified Carbidopa-to-Levodopa ratio.

5. Why Use Carbidopa & Levodopa Tablets?

The combination increases delivery of Levodopa to the central nervous system while reducing its peripheral conversion.

  • Levodopa: Crosses the blood-brain barrier and is converted to dopamine in the brain.
  • Carbidopa: Inhibits peripheral aromatic L-amino acid decarboxylase and reduces conversion of Levodopa to dopamine outside the central nervous system, allowing more Levodopa to reach the brain and reducing certain peripheral adverse effects.

Key Indications:

  • Parkinson’s Disease: Used for symptomatic management of Parkinsonian motor features such as bradykinesia and rigidity, with effects on tremor varying among patients.
  • Parkinsonism: May be used for certain forms of symptomatic parkinsonism according to approved prescribing information.

6. Export and Regulatory Support

  • Dossier: CTD and ACTD formats available where applicable.
  • Certificates: Free Sale Certificate (FSC) and COPP supplied where applicable.
  • Logistics: Shipping via FOB Mumbai or CIF.

7. Frequently Asked Questions

Q: Who manufactures Carbidopa Levodopa Tablets?
A: Healthy Life Pharma Pvt. Ltd. manufactures them in India.

Q: Do you make CR (Controlled Release) formulations?
A: Controlled-release formulations can be manufactured subject to validated formulation, market and regulatory requirements.

Q: Why is high-barrier packaging used?
A: Appropriate high-barrier packaging helps protect the formulation from moisture, oxygen and light according to its validated stability requirements.


Clinical Pharmacology & Safety Information

(For Registered Medical Practitioners & Patient Reference)

8. Dosage and Administration

  • Initiation & Titration: Dosing is individualized according to the patient’s previous therapy, symptoms, response and tolerability. Initiation and dose changes should follow approved prescribing information and medical supervision.
  • Administration: Food, particularly high-protein meals, can affect Levodopa absorption in some patients. Patients should follow a consistent dosing and meal schedule as advised by their healthcare professional.
  • Formulation: Immediate-release and controlled-release products have different release characteristics and should not be substituted without appropriate medical guidance.

9. Side Effects and Precautions

  • Dyskinesia: Involuntary movements can occur and may require dose adjustment.
  • Nausea: Gastrointestinal adverse effects may occur, particularly during initiation.
  • Neuropsychiatric Effects: Hallucinations, confusion, sleepiness or other behavioral changes can occur in some patients.
  • Body Fluid Discoloration: Levodopa metabolites can cause dark discoloration of urine, sweat or saliva; patients should discuss unexpected changes with their clinician.
  • Withdrawal: Treatment should not be stopped or substantially reduced abruptly without medical supervision.

10. Storage Instructions

  • Store below 25°C in a dry place.
  • Keep tightly closed and protect from air, moisture and light according to the product packaging requirements.
  • Keep out of reach of children.