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Lisinopril Tablets

Lisinopril Tablets

Composition: Lisinopril IP 2.5 mg; Lisinopril IP 5 mg; Lowpril Lisinopril Dihydrate BP equivalent to Lisinopril Anhydrous 20 mg

Usage: Hypertension and heart failure; selected post-heart-attack patients

Category: Anti Hypertensive / Cardiac Drugs

Therapeutic category: ACE Inhibitor / Antihypertensive

SKU: Lisinopril Tablets

Categories: Pharmaceutical Exporter India, Pharmaceutical Formulations India, WHO GMP Certified Formulations

Product Information

Lisinopril Tablets is listed in our pharmaceutical product portfolio for business-to-business enquiries. Product-specific formulation details, available strengths, dosage form, pack configuration and supply terms should be confirmed against the current product specification before ordering.

For distributor, wholesaler, hospital procurement and export enquiries, please request the applicable product specifications, batch documentation, shelf-life information, packaging options and regulatory documents. Availability and documentation depend on the product and destination market.

Description

1. Product Introduction

Lisinopril Tablets are prescription angiotensin-converting enzyme (ACE) inhibitors used for high blood pressure and selected patients with heart failure. Lisinopril may also be prescribed after an acute myocardial infarction in eligible, clinically stable patients. The supplied formulations include Lisinopril IP 2.5 mg, Lisinopril IP 5 mg and Lowpril Lisinopril BP 20 mg (expressed as anhydrous lisinopril equivalent).

Manufacturer stated: Healthy Life Pharma Pvt. Ltd.   Exporter stated: Healthy Inc. Verify facility credentials, registrations and supply terms before publication or procurement.

2. Product Specifications

Product nameLisinopril Tablets
BrandLowpril (20 mg BP formulation)
IP compositionEach film-coated tablet contains Lisinopril IP 2.5 mg or 5 mg
BP compositionEach film-coated Lowpril tablet contains Lisinopril Dihydrate BP equivalent to Lisinopril Anhydrous 20 mg
Confirmed strengths2.5 mg / 5 mg / 20 mg
Dosage formFilm-coated oral tablet
Therapeutic classACE inhibitor / Antihypertensive / Cardiovascular agent
UsesHypertension, selected heart-failure regimens, and selected post-myocardial-infarction patients
SKULisinopril Tablets
Packaging / shelf lifeConfirm with the approved product label and stability data

3. Manufacturing Technology

Film-coated lisinopril tablets require a validated formulation process to maintain consistent content uniformity, tablet hardness, disintegration and dissolution. Manufacturing methods may involve controlled blending, compression and film coating according to the registered formulation. Specific manufacturing equipment, excipients and production methods should be confirmed against site records before making public claims.

4. Quality Assurance

Typical finished-product controls include identification, assay, content uniformity, dissolution, related substances, microbial quality where applicable, and stability testing. Acceptance criteria depend on the relevant pharmacopoeial monograph and approved specifications. Batch-level Certificates of Analysis, GMP evidence and registration documents must be verified.

5. Pharmacology and Clinical Use

Lisinopril inhibits angiotensin-converting enzyme, reducing angiotensin II formation and aldosterone activity. This relaxes blood vessels, lowers blood pressure and can reduce cardiac workload.

  • Hypertension: Blood-pressure control as part of an individualized treatment plan.
  • Heart failure: May be used with other appropriate therapies under medical supervision.
  • After myocardial infarction: Used in selected hemodynamically stable patients according to prescribing guidance.

It is not an antiarrhythmic drug and is not a substitute for emergency treatment of chest pain.

6. Export and Regulatory Support

Prospective buyers may request product specifications, COA, applicable GMP documentation, stability information and regulatory dossier support, subject to availability and destination-country requirements. WHO-GMP, COPP, FSC and market authorization claims must be substantiated for the specific product and facility.

7. Frequently Asked Questions

Q: Which strengths are specified?
A: Lisinopril IP 2.5 mg, Lisinopril IP 5 mg and Lowpril BP 20 mg equivalent to anhydrous lisinopril.

Q: Is Lowpril a different active ingredient?
A: No. The supplied Lowpril formulation contains lisinopril dihydrate equivalent to 20 mg anhydrous lisinopril.

Q: Can it be used during pregnancy?
A: No. Medicines acting on the renin–angiotensin system can harm or kill a developing fetus. Contact a healthcare professional promptly if pregnancy occurs.

Q: Does it require blood tests?
A: Kidney function and potassium are commonly monitored, especially after initiation or dose changes.

8. Dosage and Administration

Take only as prescribed. The dose is individualized according to indication, blood pressure, kidney function, other medicines and patient characteristics. Lisinopril is generally taken orally once daily, with or without food, as directed by the approved label. Do not change the dose or stop treatment without medical advice. Kidney impairment can require dose adjustments.

9. Side Effects and Precautions

  • Pregnancy warning: Can cause fetal injury or death; discontinue promptly under medical direction if pregnancy is detected.
  • Angioedema: Swelling of the face, lips, tongue or throat can be life-threatening and requires emergency care.
  • Blood pressure and kidney effects: Dizziness, low blood pressure and changes in renal function may occur.
  • High potassium: Risk rises with potassium supplements, potassium-sparing diuretics and certain other medicines.
  • Other effects: Dry cough, headache and fatigue may occur.
  • Interactions: Do not combine with sacubitril/valsartan within the required 36-hour separation; certain other renin–angiotensin medicines and NSAIDs also require caution.

10. Storage Instructions

Keep in the original labeled packaging, protected from moisture and excessive heat as directed by the approved market-specific label. The exact temperature limit and shelf life must be confirmed against registered stability data. Keep out of reach of children.