Propranolol Tablets BP & – Manufacturer India

1. Product Introduction

Propranolol Hydrochloride Tablets BP contain a nonselective beta-adrenergic blocker used in the management of hypertension and selected cardiovascular and neurological conditions. The supplied formulations are 10 mg and 40 mg uncoated tablets.

Manufacturer (as supplied): Healthy Life Pharma Pvt. Ltd. Exporter (as supplied): Healthy Inc. CIRPROL is the supplied brand reference for the 40 mg formulation; trademark and product registration should be verified.

2. Product Specifications

3. Manufacturing and Formulation

Tablet manufacturing requires validated material controls, blending, compression and in-process checks to achieve consistent dosage-unit uniformity and physical quality. Specific manufacturing equipment, GMP certification and production location should be substantiated by current documentation rather than presumed.

4. Quality Assurance

Applicable quality controls may include identity, assay, dosage-unit uniformity, dissolution or disintegration, related substances and tablet integrity. Test methods and acceptance criteria must follow the relevant approved BP monograph and validated product specifications; no unverified release percentages are asserted.

5. Mechanism and Therapeutic Uses

Propranolol blocks beta-1 and beta-2 adrenergic receptors, lowering heart rate and reducing some effects of adrenaline. Depending on local product authorization, uses can include hypertension, angina, certain tachyarrhythmias, migraine prevention and essential tremor. It is not a treatment for an acute migraine attack. Other uses require clinician assessment and locally approved prescribing information.

6. Export and Regulatory Support

For contract manufacturing and export enquiries, request product approvals, current manufacturing licenses, GMP certificates, certificates of analysis, approved labels, stability data and destination-country registration requirements. Availability of CTD/ACTD dossiers, COPP, FSC, and shipping terms should be confirmed directly with the supplier.

7. Frequently Asked Questions

Q: What strengths are listed? A: Propranolol Hydrochloride BP 10 mg and 40 mg uncoated tablets.

Q: Is CIRPROL a formulation? A: CIRPROL is supplied as a brand reference for the 40 mg tablet; brand ownership and availability require verification.

Q: Can propranolol be stopped suddenly? A: No. Abrupt withdrawal may worsen angina or precipitate other cardiac problems; discontinuation should be medically supervised.

8. Dosage and Administration

Use only under the direction of a qualified prescriber. Dose and frequency vary by indication, age, pulse, blood pressure, liver function and other medicines. The supplied tablets are immediate-release uncoated products unless approved labeling states otherwise. Do not substitute extended-release and immediate-release formulations without clinical advice.

9. Side Effects and Precautions

Potential effects include fatigue, dizziness, bradycardia, low blood pressure, cold extremities and sleep disturbances. Important warnings: Propranolol may cause bronchospasm and is generally unsuitable for patients with asthma or certain obstructive airway conditions; it can mask warning signs of hypoglycemia in diabetes. Contraindications may include significant bradycardia, heart block and cardiogenic shock. Interactions with other heart-rate-lowering drugs require medical review. Do not stop suddenly.

10. Storage Instructions

Store according to the approved product label in original packaging, protected from conditions specified by the manufacturer. Keep out of reach of children. Do not publish a fixed shelf life or temperature threshold without validated labeling.